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NEUROTHERAPY FOR OBSESSIVE COMPULSIVE DISORDER (OCD): RESEARCH

Research shows that neurotherapy may significantly reduce symptoms, improve emotional stability, and enhance overall well-being by targeting the brainwave imbalances associated with obsessive-compulsive disorder (OCD).  At Transformative Neurotherapy, we welcome curiosity and invite those who want to dig deeper to explore the research behind our methods, including Neurostimulation and Photobiomodulation (PBM) — all grounded in science that supports their effectiveness in improving mental health.

    • Adams, T. G., Cisler, J. M., Kelmendi, B., George, J. R., Kichuk, S. A., Averill, C. L., Anticevic, A., Abdallah, C. G., & Pittenger, C. (2021). Transcranial direct current stimulation targeting the medial prefrontal cortex modulates functional connectivity and enhances safety learning in obsessive-compulsive disorder: Results from two pilot studies. Depression and Anxiety, 39(1), 37–48. https://doi.org/10.1002/da.23212

    • Adams, T. G., Jr., Rippey, C. S., Kelly, A. R., Gold, B. T., & Pittenger, C. (2021). Treatment of obsessive-compulsive disorder with frontopolar multifocal transcranial direct current stimulation and exposure and response prevention: A case series. Brain Stimulation, 14(6), 1431-1433. doi: 10.1016/j.brs.2021.09.008

    • Brunelin J, Mondino M, Bation R, Palm U, Saoud M, Poulet E. Transcranial Direct Current Stimulation for Obsessive-Compulsive Disorder: A Systematic Review. Brain Sci. 2018 Feb 24;8(2):37. doi: 10.3390/brainsci8020037. PMID: 29495298; PMCID: PMC5836056.

    • Gao, J., Jia, W., Li, P. et al. Transcranial direct current stimulation enhances exposure–response prevention for contamination-related OCD: a randomized clinical trial. Nat. Mental Health 3, 507–516 (2025). https://doi.org/10.1038/s44220-025-00410-w

    • Kammen A, Cavaleri J, Lam J, Frank AC, Mason X, Choi W, Penn M, Brasfield K, Van Noppen B, Murray SB, Lee DJ. Neuromodulation of OCD: A review of invasive and non-invasive methods. Front Neurol. 2022 Aug 9;13:909264. doi: 10.3389/fneur.2022.909264. PMID: 36016538; PMCID: PMC9397524.

    • Pellegrini L, Albert U. Transcranial direct current stimulation (tDCS) in obsessive compulsive disorder (OCD): the state of the art. Italian Journal of Psychiatry. 2024; 10:32-34; doi: 10.36180/2421-4469-2024-7

    • Rapinesi C, Kotzalidis GD, Ferracuti S, Sani G, Girardi P, Del Casale A. Brain Stimulation in Obsessive-Compulsive Disorder (OCD): A Systematic Review. Curr Neuropharmacol. 2019;17(8):787-807. doi: 10.2174/1570159X17666190409142555. PMID: 30963971; PMCID: PMC7059162.

    • Shivakumar V, Dinakaran D, Narayanaswamy JC, Venkatasubramanian G. Noninvasive brain stimulation in obsessive-compulsive disorder. Indian J Psychiatry. 2019 Jan;61(Suppl 1):S66-S76.doi: 10.4103/psychiatry.IndianJPsychiatry_522_18 PMID: 30745679; PMCID: PMC6343411.

    • Coelho DRA, Salvi JD, Vieira WF, Cassano P. Inflammation in obsessive-compulsive disorder: A literature review and hypothesis-based potential of transcranial photobiomodulation. J Neurosci Res. 2024 Mar;102(3):e25317. doi: 10.1002/jnr.25317 PMID: 38459770.

What Neurotherapy treatments does Transformative Neurotherapy offer?

“Neurotherapy” or “Neuromodulation” is a broad term for a number of different types of treatment options. We’ve outlined below what Transformative Neurotherapy does and does not currently offer.

A table comparing types of neurotherapy offered by Transformative Neurotherapy, with symbols indicating which types are provided. The table shows check marks for most types and crosses for some, with three entries marked with stars indicating other categories.